DNA Repair Drugs Market SWOT Analysis, Segmentation, Applications & Emerging Audience Till 2026

DNA can be damaged
due to endogenous factors (oxidation) or exogenous factors (UV
radiations or viruses), but our cell can identify and repair the
damage. However, when the repairing mechanism of the cell fails, it
leads to dysfunctionality or mutations in the DNA of the cell. It can
also lead to abnormal growth of cells, i.e., cancer. Such irreparable
damage can be treated with DNA repair drugs such as poly ADP-ribose
polymerase inhibitors (PARP). PARP blocks the activity of ADP-ribose
polymerase proteins, thus preventing the replication of cancer cells.
Global DNA Repair
Drugs Market Drivers
Increasing
collaboration and acquisition activities are expected to boost the
global DNA
repair drugs market growth. For instance, in January 2017,
Merck KGaA entered into a licensed agreement with Vertex
Pharmaceuticals Inc., for four research developments on approaches to
cancer. The reason for the partnership was to strengthen Merck’s
area of DNA damage response and immuno-oncology. Furthermore, in
February 2016, Onxeo, an orphan oncology therapeutics company,
acquired DNA Therapeutics, a biopharmaceutical company for its DNA
repairing technology for treatment of cancer. This technology
consists of a signal interfering DNA molecule (siDNA), and Onxeo S.A.
intends to develop this technology as a potential treatment option
for cancer. Such partnerships are expected to propel the global DNA
repair drugs market growth.
Global DNA Repair
Drugs Market Regional Analysis
North America is
expected to hold a dominant position in the global DNA repair drugs
market. Factors such as increasing research and development
activities are expected to have an influence on the North America’s
DNA repair drugs market growth. For instance, in 2017, Harvard
Medical School and University of South Wales conducted a study on DNA
repair drugs for treatment of radiation damage that causes cancer.
They have discovered the mechanism that weakens the system of our
cell’s capability to repair the damages. They developed a drug,
which was tested on mice and the mice were successfully able to
retrieve the cell functions. The successful development of such
researches is expected to propel the global DNA repair drug market
growth.
Global DNA Repair
Drugs Market Restraints
Failure of drugs in
late stages of clinical trials has hampered the global DNA repair
drugs market growth. For instance, in April 2017, Veliparib, a
product by AbbVie was withdrawn from both the clinical trial studies.
One of the clinical trial study involved the drug’s efficacy on
breast cancer and other for lung cancer. Veliparib was treated with a
combination of chemotherapy for both, lung and breast cancer
treatment. Both of the trials were withdrawn at its third phase. Such
failures may hinder the global DNA repair drugs market growth.
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Global DNA Repair
Drugs Market Key Players
Some of the major
players operating in the global DNA repair drugs market include 4SC
AG, Artios Pharma, Johnson & Johnson Service Inc.,
GlaxoSmithKline plc, Genentech, Inc., Sierra Oncology Inc.,
AstraZeneca, Karyopharm Therapeutics, Jiangsu Hengrui Medicine Co.,
Ltd., and Merck KGaA.
Global DNA Repair
Drugs Market Taxonomy
The global DNA
repair drugs market is segmented on the basis of drug, application,
distribution channels, and regions.
By Drug
Niraparib
(Zejula)
Olaparib
(Lynparza)
Rucaparib
(Rubraca)
Talazoparib
(Talzenna)
Others
By Application
Ovarian cancer
Fallopian tube
cancer
Peritoneal
cancer
Breast cancer
Gastric cancer
By Distribution
Channel
Hospital
pharmacies
Retail
pharmacies
Online
pharmacies
By Region
North America
Latin America
Europe
Asia Pacific
Middle East
Africa
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