healthCMI

DNA can be damaged due to endogenous factors (oxidation) or exogenous factors (UV radiations or viruses), but our cell can identify and repair the damage. However, when the repairing mechanism of the cell fails, it leads to dysfunctionality or mutations in the DNA of the cell. It can also lead to abnormal growth of cells, i.e., cancer. Such irreparable damage can be treated with DNA repair drugs such as poly ADP-ribose polymerase inhibitors (PARP). PARP blocks the activity of ADP-ribose polymerase proteins, thus preventing the replication of cancer cells. Global DNA Repair Drugs Market Drivers Increasing collaboration and acquisition activities are expected to boost the global DNA repair drugs market growth. For instance, in January 2017, Merck KGaA entered into a licensed agreement with Vertex Pharmaceuticals Inc., for four research developments on approaches to cancer. The reason for the partnership was to strengthen Merck’s area of DNA damage response and i...